Computational Biology

2 posts

Side-by-side visual: on the left, an AI structural prediction rendered as rigid clockwork gears with pLDDT 95.3 high confidence; on the right, fluid intrinsically disordered protein regions with regulator molecules, signaling molecules, and PTMs flowing around DNA strands. Tagline reads 'AI sees structure. Biology runs on motion.'

AI Drug Discovery·April 20, 2026·6 min read

Why Your AI Is Reading the Wrong Half of the Protein

AlphaFold's low-confidence regions aren't always errors — many are intrinsically disordered, where the absence of stable structure IS the function. Why pipelines that penalize disorder systematically misread half the proteome.

Two professionals in a futuristic lab — a tech-styled figure in a cap and headphones sitting next to a scientist in a white coat and safety glasses — surrounded by holographic molecular structures, AI visualizations, and flasks on a workbench, with the words 'Geek Life' across the image

AI Drug Discovery·April 20, 2026·6 min read

Uniting Tech and Science Geeks: Three Plays for AI-Driven Drug Discovery

AI drug discovery's hardest problem isn't a model — it's a coordination problem between engineers who don't speak biology and biologists who don't ship code. Three high-leverage plays for bridging the two cultures.